BREYANZI is a prescription medicine used to treat large B cell lymphoma, a type of non-Hodgkin lymphoma, when:
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Each step of your treatment is important. Your healthcare team will help you throughout treatment and monitoring. They can answer any questions you may have about Breyanzi.
Everyone is different, and the time it takes to complete the Breyanzi CAR T cell therapy process may vary.
Your white blood cells will be collected through a process called apheresis (sometimes called leukapheresis)
Your blood is drawn and the components are separated into groups. Your T cells are collected and the other parts of your blood are returned back into your body.
Apheresis can be done in 1 day and usually takes 2 to 6 hours.
Your T cells will be sent to a manufacturing site
While at the manufacturing site, chimeric antigen receptors (CARs) are added to your T cells to make the Breyanzi CAR T cells that are unique to you.
During this time, you may receive other treatments for the cancer.
Before your Breyanzi infusion, you’ll receive low-dose chemotherapy
You’ll receive 3 days of a low-dose of chemotherapy, called lymphodepleting chemotherapy, to help prepare your body for Breyanzi.
You'll receive Breyanzi as infusions of 2 different cell types
Breyanzi is given as infusions of 2 different cell types. These infusions are given one after the other, and each takes less than 15 minutes to infuse, but times may vary.
Breyanzi will be given at an authorized treatment center by a specially trained healthcare team. Your healthcare provider will decide if you need to stay in the hospital or if you can be discharged after treatment.
You'll be closely monitored for side effects following your Breyanzi infusion
During the first week, you will be monitored daily by the facility where you received Breyanzi. Plan to stay close to this location for at least 4 weeks after infusion.
You may be hospitalized for side effects and your healthcare provider will discharge you if your side effects are under control, and it is safe for you to leave.
Your healthcare provider will want to do blood tests to follow your progress. It is important that you have your blood tested. If you miss an appointment, call your healthcare provider as soon as possible to reschedule.
Because of the risk of side effects that are life-threatening and can lead to death, Breyanzi is only available at authorized treatment centers and must be infused by specially trained healthcare teams.