BREYANZI is a prescription medicine used to treat large B cell lymphoma, a type of non-Hodgkin lymphoma, when:

  • your first treatment has not worked or your cancer returned within a year of your first treatment OR...Read more

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Helping you care for someone receiving Breyanzi®

The typical CAR T cell therapy process can take 2 to 3 months of treatment and initial follow-up monitoring. During this time, you may help the person you’re caring for in many ways

Hypothetical Breyanzi® (lisocabtagene maraleucel) care partner writing

Staying organized

  • Ask questions at any point during treatment

  • Bring important information (list of allergies and other medication the person you’re caring for is taking) to appointments

  • Keep the healthcare team’s contact information in a convenient place

Hypothetical Breyanzi® (lisocabtagene maraleucel) care partner cooking

Assisting with practical support

  • Schedule upcoming appointments

  • Transportation to appointments

  • Relay medical and insurance information to the healthcare team

  • Refill prescriptions

  • Meals, laundry, and cleaning

  • Managing visitors

  • You and the person you are caring for should plan to stay close to the location where they received Breyanzi for at least 4 weeks following treatment

  • The person you’re caring for should not drive, operate heavy machinery, or do other activities that could be dangerous for at least 8 weeks after receiving treatment.
    The person you’re caring for should not donate blood, organs, tissues, or cells for transplantation

Hypothetical Breyanzi® (lisocabtagene maraleucel) patient receiving CAR T cell therapy and their care partner

Providing medical support

  • Call 911 or the person’s healthcare team in the event of a medical emergency or if they show signs of a serious side effect

  • Accompany the person throughout their Breyanzi treatment

  • Check the person’s temperature regularly following treatment

    • Call the healthcare provider or go to the hospital if the temperature is 100.4˚F/38.0˚C or higher

  • Watch for symptoms, side effects, and other changes in health or behavior

Hypothetical Breyanzi® (lisocabtagene maraleucel) patient and their care partner monitoring side effects

Monitoring for side effects

When the person you’re caring for has received their treatment, their healthcare provider will tell you which side effects to watch out for.

Breyanzi may cause side effects that are life-threatening and can lead to death. As the care partner, you will need to be able to recognize if the person needs help and know how to respond appropriately in emergencies and urgent situations.

Learn when to call your healthcare provider or get emergency help
Hypothetical Breyanzi® (lisocabtagene maraleucel) care partner walking dog

Remember self-care

You’re an essential part of the care team for the person you’re looking after, and taking on the role can be demanding. It’s important to practice self-care and make time for yourself.

  • Make sure you’re getting enough rest

  • Eat consistent meals and stay hydrated

  • Reach out for support

Become familiar with the Breyanzi treatment process to know what to expect every
step of the way.

LEARN MORE

Important Safety Information

What is the most important information I should know about BREYANZI?

BREYANZI may cause side effects that are life-threatening and can lead to death. Call your healthcare provider or get emergency help right away if you get any of the following:

  • difficulty breathing

  • fever (100.4°F/38°C or higher)

  • chills/shaking chills

  • confusion

  • severe nausea, vomiting, diarrhea

  • fast or irregular heartbeat

  • dizziness/lightheadedness

  • severe fatigue or weakness

It is important that you tell your healthcare providers that you have received BREYANZI and to show them your BREYANZI Patient Wallet Card. Your healthcare provider may give you other medicines to treat your side effects.

Before getting BREYANZI, tell your healthcare provider about all your medical problems, including if you have or have had:

  • Neurologic problems (such as seizures, stroke, or memory loss)

  • Lung or breathing problems

  • Heart problems

  • Liver problems

  • Kidney problems

  • A recent or active infection

Tell your healthcare provider about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How will I receive BREYANZI?

  • BREYANZI is made from your own white blood cells, so your blood will be collected by a process called leukapheresis.

  • It takes about 3-4 weeks from the time your cells are received at the manufacturing site and are available to be shipped back to your healthcare provider, but the time may vary.

  • Before you get BREYANZI, you will get 3 days of chemotherapy to prepare your body.

  • When your BREYANZI is ready, your healthcare provider will give it to you through a catheter placed into your vein. BREYANZI is given as infusions of 2 different cell types.

    • You will receive infusions of one cell type, immediately followed by the other cell type.

    • The time for infusion will vary, but will usually be less than 15 minutes for each of the 2 cell types.

  • During the first week, you will be monitored daily by the facility where you received your treatment.

  • You should plan to stay close to this location for at least 4 weeks after getting BREYANZI. Your healthcare provider will check to see that your treatment is working and help you with any side effects that may occur.

  • You may be hospitalized for side effects and your healthcare provider will discharge you if your side effects are under control, and it is safe for you to leave the hospital.

  • Your healthcare provider will want to do blood tests to follow your progress. It is important that you have your blood tested. If you miss an appointment, call your healthcare provider as soon as possible to reschedule.

What should I avoid after receiving BREYANZI?

  • Do not drive, operate heavy machinery, or do other activities that could be dangerous if you are not mentally alert, for at least 8 weeks after you get BREYANZI. This is because the treatment can cause temporary memory and coordination problems, including sleepiness, confusion, dizziness, and seizures.

  • Do not donate blood, organs, tissues, or cells for transplantation.

What are the possible or reasonably likely side effects of BREYANZI?

The most common side effects of BREYANZI are:

  • fatigue

  • difficulty breathing

  • fever (100.4°F/38°C or higher)

  • chills/shaking chills

  • confusion

  • difficulty speaking or slurred speech

  • severe nausea, vomiting, diarrhea

  • headache

  • dizziness/lightheadedness

  • fast or irregular heartbeat

  • swelling

BREYANZI can increase the risk of life-threatening infections that may lead to death. Tell your healthcare provider right away if you develop fever, chills, or any signs or symptoms of an infection.

BREYANZI can lower one or more types of your blood cells (red blood cells, white blood cells, or platelets). After treatment, your healthcare provider will test your blood to check for this. Tell your healthcare provider right away if you get a fever, are feeling tired, or have bruising or bleeding.

Having BREYANZI in your blood may cause a false-positive HIV test result by some commercial tests.

These are not all the possible side effects of BREYANZI. Call your doctor for medical advice about side effects. For more information, go to BREYANZI.com or call 1-888-805-4555. You may report side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed WARNINGS and Medication Guide.

Indication

BREYANZI is a prescription medicine used to treat large B cell lymphoma, a type of non-Hodgkin lymphoma, when:

  • your first treatment has not worked or your cancer returned within a year of your first treatment OR

  • your first treatment has not worked or your cancer returned after the first treatment, and you are not eligible for hematopoietic stem cell transplantation because of medical conditions or age OR

  • two or more kinds of treatment have not worked or stopped working.

BREYANZI is different than other cancer medicines because it is made from your own white blood cells, which have been genetically modified to recognize and attack your lymphoma cells.

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BREYANZI and the related logo are trademarks of Juno Therapeutics, Inc., a Bristol-Myers Squibb Company.
CELL THERAPY 360 and the related logo are trademarks of Celgene Corporation, a Bristol-Myers Squibb Company.

2009-US-2200413

12/2022