For questions about BMS medicines during this time please call 1-800-721-8909.

Breyanzi® CAR T cell therapy is different from previous cancer treatments that the person you’re caring for has received.

Breyanzi is an infusion of their reprogrammed white blood cells, or T cells. Your involvement throughout their treatment process is important. But you won’t be alone. You will be working closely with the healthcare team to help manage their care.

The typical CAR T process can take approximately 2 to 3 months of treatment and initial follow-up monitoring. During this time, you may help the person you’re caring for in many ways.

Care Partner logging side effects

Staying organized

  • Ask questions at any point during treatment
  • Bring important information (list of allergies and other medication the person you’re caring for is taking) to appointments
  • Keep the healthcare team’s contact information in a convenient place
Care Partner Cooking

Assisting with practical support

  • Schedule upcoming appointments
  • Transportation to appointments
  • Relay medical and insurance information to the healthcare team
  • Refill prescriptions
  • Meals, laundry, and cleaning
  • Managing visitors
  • During the first week, the person you're caring for will be monitored daily by the facility where they received their treatment. You and the person you’re caring for should plan to stay close to the location where they received Breyanzi for at least 4 weeks following treatment
  • The person you’re caring for should not drive, operate heavy machinery, or do other activities that could be dangerous for at least 8 weeks after receiving treatment. This is because the treatment can cause temporary memory and coordination problems, including sleepiness, confusion, dizziness, and seizures. They should also not donate blood, organs, tissues, or cells for transplantation
Care Partner Sitting with Loved One During Infusion

Providing medical support

  • Call 911 or the person’s healthcare team in the event of a medical emergency or if they show signs of a serious side effect
  • Accompany the person throughout their Breyanzi treatment
  • Check the person’s temperature regularly following treatment
    • Call the healthcare provider or go to the hospital if the temperature is 100.4˚F/38.0˚C or higher
  • Watch for symptoms, side effects, and other changes in health or behavior
Care Partner Monitoring for Fever

Monitoring for side effects

When the person you’re caring for has received their treatment, their healthcare provider will tell you which side effects to watch out for.

Breyanzi may cause side effects that are life-threatening and can lead to death. As the care partner, you will need to be able to recognize if the person needs help and know how to respond appropriately in emergencies and urgent situations.

Learn about when to call a healthcare provider or get emergency help >

Care Partner Going for a Walk

Remember self-care

You’re an essential part of the care team for the person you’re looking after, and taking on the role can be demanding. It’s important to practice self-care and make time for yourself.

  • Make sure you’re getting enough rest
  • Eat consistent meals and stay hydrated
  • Reach out for support

Become familiar with the Breyanzi treatment process to know what to expect every step of the way

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Important Safety Information

What is the most important information I should know about BREYANZI?

BREYANZI may cause side effects that are life-threatening and can lead to death. Call your healthcare provider or get emergency help right away if you get any of the following:

  • difficulty breathing
  • fever (100.4°F/38°C or higher)
  • chills/shaking chills
  • confusion
  • severe nausea, vomiting, diarrhea
  • fast or irregular heartbeat
  • dizziness/lightheadedness
  • severe fatigue or weakness

Important Safety Information

What is the most important information I should know about BREYANZI?

BREYANZI may cause side effects that are life-threatening and can lead to death. Call your healthcare provider or get emergency help right away if you get any of the following:

  • difficulty breathing
  • fever (100.4°F/38°C or higher)
  • chills/shaking chills
  • confusion
  • severe nausea, vomiting, diarrhea
  • fast or irregular heartbeat
  • dizziness/lightheadedness
  • severe fatigue or weakness

It is important that you tell your healthcare providers that you have received BREYANZI and to show them your BREYANZI Patient Wallet Card. Your healthcare provider may give you other medicines to treat your side effects.

How will I receive BREYANZI?

  • BREYANZI is made from your own white blood cells, so your blood will be collected by a process called leukapheresis.
  • It takes about 3-4 weeks from the time your cells are received at the manufacturing site and are available to be shipped back to your healthcare provider, but the time may vary.
  • Before you get BREYANZI, you will get 3 days of chemotherapy to prepare your body.
  • When your BREYANZI is ready, your healthcare provider will give it to you through a catheter placed into your vein. BREYANZI is given as infusions of 2 different cell types.
    • You will receive infusions of one cell type, immediately followed by the other cell type.
    • The time for infusion will vary, but will usually be less than 15 minutes for each of the 2 cell types.
  • During the first week, you will be monitored daily by the facility where you received your treatment.
  • You should plan to stay close to this location for at least 4 weeks after getting BREYANZI. Your healthcare provider will check to see that your treatment is working and help you with any side effects that may occur.
  • You may be hospitalized for side effects and your healthcare provider will discharge you if your side effects are under control, and it is safe for you to leave the hospital.
  • Your healthcare provider will want to do blood tests to follow your progress. It is important that you have your blood tested. If you miss an appointment, call your healthcare provider as soon as possible to reschedule.

What should I avoid after receiving BREYANZI?

  • Do not drive, operate heavy machinery, or do other activities that could be dangerous if you are not mentally alert, for at least 8 weeks after you get BREYANZI. This is because the treatment can cause temporary memory and coordination problems, including sleepiness, confusion, dizziness, and seizures.
  • Do not donate blood, organs, tissues, or cells for transplantation.

What are the possible or reasonably likely side effects of BREYANZI?

The most common side effects of BREYANZI are:

  • fatigue
  • difficulty breathing
  • fever (100.4°F/38°C or higher)
  • chills/shaking chills
  • confusion
  • difficulty speaking or slurred speech
  • severe nausea, vomiting, diarrhea
  • headache
  • dizziness/lightheadedness
  • fast or irregular heartbeat
  • swelling

BREYANZI can increase the risk of life-threatening infections that may lead to death. Tell your healthcare provider right away if you develop fever, chills, or any signs or symptoms of an infection.

BREYANZI can lower one or more types of your blood cells (red blood cells, white blood cells, or platelets). After treatment, your healthcare provider will test your blood to check for this. Tell your healthcare provider right away if you get a fever, are feeling tired, or have bruising or bleeding.

Having BREYANZI in your blood may cause a false-positive HIV test result by some commercial tests.

These are not all the possible side effects of BREYANZI. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed WARNINGS and Medication Guide.

Indication

BREYANZI is for the treatment of large B-cell lymphoma in patients when at least 2 previous treatments have not worked or have stopped working. BREYANZI is a medicine made from your own white blood cells; the cells are genetically modified to recognize and attack your lymphoma cells.